RNASE R, A NEW VIRULENCE DETERMINANT OF STREPTOCOCCUS PNEUMONIAE

RNase R, a New Virulence Determinant of Streptococcus pneumoniae

Pneumococcal infections have increasingly high mortality rates despite the super speciosa sale availability of vaccines and antibiotics.Therefore, the identification of new virulence determinants and the understanding of the molecular mechanisms behind pathogenesis have become of paramount importance in the search of new targets for drug developmen

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Prospective randomized comparative study between EBRT alone and EBRT with ILRT boost in locally advanced unresectable esophageal cancer - Tertiary rural Indian cancer center experience

Background: Local recurrence within the gross tumor volume following a conventional radiation dose of 50 Gy is a major hurdle in achieving a better prognosis for esophageal carcinoma.Consequently, there remains a lack of consensus globally regarding the optimal dose for definitive concurrent chemoradiotherapy.Certain studies propose that radiation

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The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration

Objectives: Human Urinary Kallidinogenase (HUK) is a tissue kallikrein that plays neuroprotective role in ischemic conditions via different mechanisms.Mild hypothermia (MH) is another robust neuroprotectant that reduces mortality but does not profoundly ameliorate the neurological outcome in hypoxic-ischemic encephalopathy (HIE) patients.However, w

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Selecting Key Smart Building Technologies for UAE Prisons by Integrating Analytical Hierarchy Process (AHP) and Fuzzy-TOPSIS

Prisons are the structures used for incarcerated inmates and are often overcrowded and understaffed.This often leads to inhumane conditions and increased violence.Smart building technologies can help to yocan cubex coils alleviate these problems to some extent and improve communication between staff and prisoners.However, selecting appropriate smar

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Are Aminoglycoside Antibiotics TRPing Your Metabolic Switches?

Transient receptor potential (TRP) channels are broadly implicated in the developmental programs of most tissues.Amongst these tissues, skeletal muscle and adipose are noteworthy for being essential in establishing systemic metabolic balance.TRP junk ear warmer channels respond to environmental stimuli by supplying intracellular calcium that instig

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